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. Cyclin-dependent kinase 14 promotes cell proliferation, migration and invasion in ovarian cancer by inhibiting Wnt signaling pathway. Gene expression regulation by CDK12: a versatile kinase in cancer with capabilities over and above CTD phosphorylationBlocking the conserved ATP binding web-site is the most common mechanism to inhibit the kinase,

Identification from the “viral entry” inhibitors might be visualized by using the effect comparing for HBV infecting in the cultivated HepG2/NTCP cells before and after the analyzed compound adding.Structures of Tyr188Leu mutant and wild-style HIV-1 reverse transcriptase complexed Along with the non-nucleoside inhibitor HBY 097: inhibitor versa